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  • The Uplift Project, Andrea Praet curates and produces events and experiences that are transformative for the mind, body and spirit. He is also the NYC head of production for The Shine Movement, a mindful variety show that inspires individuals to do more.


  • Born and raised in Toronto, Canada, Katia came to New York City in 2005 to pursue graduate studies in Counseling Psychology at Columbia University. Upon graduating he served chronically mentally ill adults and later children in foster care.

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LATEST NEWS

Where to Buy Used Medical Equipment Online

There are plenty of places to buy new medical equipment; but quite frankly, they’re rather expensive, and slightly used equipment provides practically the exact same product for a much cheaper price. So, then, if you need used medical equipment–a broad term encompassing almost all items a hospital should be equipped with (gurneys, microscopes, patient monitors, autoclaves, etc., and much more)–where can you look online? Googling “used medical equipment” doesn’t help–there are too many websites to know which ones have what you need. To make matters worse, some of the websites–like–have “new and used equipment”, which complicates your search (most of their items are new). Without further ado, here are the best websites for buying used medical equipment online.

#1. PEMED

PEMED (Production Engineering Medical Equipment Division, found, has been in business for 20 years, until recently occupied the #1 Google ranking under a search for used medical equipment, and is quite simply the best used medical provider in America. While some buyers are put off by PEMED’s no-nonsense attitude– nonserious buyers are quickly recognized and turned away–for serious buyers, PEMED provides quality used medical equipment at an excellent value. Questions via phone and email are promptly returned if their user-friendly website doesn’t answer a specific question. The only knock on PEMED is that they don’t accept credit-cards–this serves to weed out the nonserious buyers, so this doesn’t concern people like you. Every item on the website is physically in stock and well-photographed. All you need to know about PEMED is found on their website:

  1. “Everything we sell is, without exception, in stock in our warehouse. Unless we’ve sold it.
  2. We grade every item according to the MedConTM condition rating system. Developed by PEMED, it is an objective way of judging the quality and condition of used equipment.
  3. We do not oversell an item. We will tell you the strengths and weaknesses of our knowledge. This is medical equipment; questions must be answered, if not by us then someone who is knowledgeable.
  4. Everything sold as is; every medical end user purchase has a 14 day no questions asked return policy.
  5. 20 years in business – 82 countries worldwide.

How do we do it? We buy over 80 truckloads of equipment each year. That’s how we bring you the largest selection and lowest prices – we guarantee it.”

PEMED should be the first website you visit when you look for used medical equipment.

#2 DotMed & MedWow

If you would prefer buying via an auction, DotMed or MedWow are the premier destinations for online auctions. The disadvantage to buying via auction is its hit-or-miss nature–the specific item you are looking for might not be listed, and there isn’t a sales manager you can email or call who can tell you what they have and don’t have, what condition it is in, etc. DotMed and MedWow are merely third-party agents–in most cases, you don’t know who the actual seller is (though you are able to contact them). Nevertheless, many good deals can be found in auctions, and either can hook you up with that one piece of equipment you desire–provided that you are patient and prepared to spend a little time searching around. MedWow’s website is better put-together; however, DotMed has been in business much longer, MedWow is based in Cyprus. I would recommend you start with DotMed, but MedWow is also a possibility.

(If you are hell-bent on buying your equipment via an auction, you can try but it seems that all they have going for them is a good Google ranking. However, I have not had personal experience with the company, so you could give it a try if you really want to.)

#3 a2z DME

Available at https://a2z-dme.com/, a2z DME provides refurbished equipment at reasonable prices. Like PEMED, they have photographs of their equipment and a very large inventory. Their user-friendly website is a very solid option as well, behind PEMED.

Those are the top websites that you should visit; it would greatly surprise me if you haven’t found what you need at those websites. There are many other websites that can provide new and used medical equipment–you could spend a few hours searching and finding the website with the lowest price on the item you desire. In general, however, you get what you pay for, and the above websites will have what you need at a reasonable price. The search for used medical equipment doesn’t need to be so complicated–with these websites, it most certainly isn’t.

IT Service Management Moves to the Cloud

IT Service Management Moves to the Cloud

IT service is an important factor when you are doing business in the modern world. Specially today, when Covid and other diseases are at our doors. It’s a time when we cant even think about stepping outside of our homes. Governments have issued total lockdown in most countries. In such situations, without the help of the cyber world, you cant really communicate with the real world. So if you are doing a business and you need to communicate with your customers then its crucial for you to ensure that the IT part of your business is working perfectly. Here comes the importance of the IT support. You can hire an IT support provider who will manage the IT part of your business. Better hire a Cloud Based IT service because they are modern and updated. Today we will learn about a Cloud Based IT support.

Holland America Line became the latest company to make the move to cloud-based IT services this month, when they selected ServiceNow as their service automation provider .

IT Service

Making the move to cloud-based services instead of in-house IT management will help reduce the number of on-site IT systems and manual tasks. It will also save the company in both IT management costs and equipment costs.

Holland America is just the latest in a number of companies to choose cloud services for IT management. Last year, Equinix faced a similar problem and found the same answer.

Just since 2007, Equinix has expanded in Europe, the United States, Brazil and Hong Kong. The IT needs spread over 31 markets and utilized six different IT delivery systems to automate services. Most of these solutions were on-site,

With cloud services, companies can cut costs while improving their ability to adjust to changing conditions in the field. In addition, experienced cloud-based service management companies can sometimes find ways to automate services that were previously considered manual tasks. This is one of the goals of the partnership between ServiceNow and Holland America.

IT Management

IT service automation began in the 1990s with companies who offered individual service solutions. As these became more and more popular, there was a move to role all of the services into suites, but these were costly and still operated as separate tools in many cases.

Most cloud-based service management solutions cost between 50 and 75 percent of the cost of their on-site predecessors, according to an interview with Jack Probst published on CIO.com . Probst serves as president-elect of Information Technology Service Management Forum USA.

There are also non-economic advantages of cloud managed services. The cloud model offers flexibility and upgrade-ability in ways never seen before in the field. As technology expands, the services offered can increase without adding the cost of investing in new equipment.

Allergic Anaphylaxis Affects on Breathing and Heart Rate

Allergic Anaphylaxis Affects on Breathing and Heart Rate

Anaphylaxis is a serious reaction usually caused by an allergen, though in some cases it can be exercise-induced. This severe allergic reaction typically occurs very rapidly and causes noticeable symptoms that affect the skin and breathing. In some cases anaphylaxis can be fatal.

Anaphylaxis is the Opposite or Prophylaxis

The term anaphylaxis was coined to mean the opposite of prophylaxis, which is defined as protection against a disease causing factor or organism.

Anaphylaxis is the Opposite or Prophylaxis

In most cases, this reaction occurs when there is a previous exposure to the allergen that causes sensitivity. When the exposure to the allergen occurs again, the immune system strongly overreacts leading to an anaphylactic reaction. The most common inciting allergens are antibiotics, particularly penicillin, intravenous dyes used in some medical scans and tests, bee sting venom and certain foods, most commonly, peanuts. In some cases there is no known cause for the anaphylactic reaction. We have provided you detail about allergic anaphylaxis; if you want to explore your knowledge, look at more info.

Breathing Effects of Anaphylaxis

Anaphylactic reactions generally involve the skin and mucous membranes in more than 90 percent of cases. This results in erythema or skin redness, urticaria or hives, pruritus or an itchy rash, and angioedema or swelling.

The reaction commonly impedes breathing because it generally affects the upper respiratory tract causing nasal congestion, sneezing, hoarseness or inability to speak. Constriction and swelling can also occur in the throat and upper bronchus of the lungs making it difficult to breathe.

Airway obstruction symptoms are extremely frightening and can cause chest pain, panic attacks, dizziness and fainting. The swelling of the lips, tongue and throat and spasms in the lung’s airways may also cause dyspnea or difficulty swallowing. Wheezing and shortness of breath occurs when the lower lungs are affected due to swelling of the tissues and mucus buildup in the airways. Complete airway obstruction is the most common cause of death due to anaphylaxis.

How Anaphylaxis Affects the Heart

Other signs include itchy and water eyes. Stomach affects such as cramp-like abdominal pain, nausea, vomiting and diarrhea, are particularly common if the anaphylactic reaction is caused by a food allergen.

How Anaphylaxis Affects the Heart

In severe cases of anaphylaxis the blood vessels dilate and the heart must beat faster to compensate for the loss of blood flow through the body. This causes tachycardia or a very fast heart beat. Blood volume decreases because fluids leak out of the capillaries causing hypotension or low blood pressure. In some cases, very low blood pressure can cause a loss of consciousness.

Children may not show visible skin signs of an anaphylactic reaction, causing a delay in medical treatment. Any degree of anaphylaxis requires immediate medical attention; remove the allergen if possible and seek urgent care.

Common Risk Factors for Developing High Blood Pressure

Common Risk Factors for Developing High Blood Pressure

High blood pressure (hypertension) can occur for many different reasons, some due to family history, race or age and other factors that a person has control of such as weight, diet and exercise. It is important to know the risk factors so the person can lower the risk of high blood pressure by simply making some lifestyle changes, check our expert reviews here.

Uncontrollable Risk Factors for High Blood Pressure

Uncontrollable Risk Factors for High Blood Pressure

A person can develop high blood pressure as they age or because of family hereditary or race. As people age, high blood pressure becomes more common, especially in men. Women may develop high blood pressure after menopause. Because high blood pressure is a problem associated with aging, it is especially important to watch the diet and to exercise to decrease the risk.

Family history and race also contribute to the risk of developing high blood pressure. People who have a family history of high blood pressure are more likely to have it also. High blood pressure is also prevalent among the black population. Black people are more likely to develop high blood pressure at a younger age than white people. If a person knows they are more likely to develop high blood pressure, it allows them the opportunity to lower their risk factors, such as weight, diet and smoking, in order to lower the chance of developing the disease.

Controllable Risk Factors for High Blood Pressure

Many of the risk factors for high blood pressure can be eliminated either through diet, adding exercise, weight control or stress control. Simply living a healthier lifestyle can lower the risk of developing high blood pressure. Controllable risk factors include:

diet contributes to weight gain

Diet – Eating a high-fat diet contributes to weight gain, another risk factor for high blood pressure. Too much salt in the diet is also unhealthy as it makes the body retain water, which increases blood pressure. Too little potassium can also be dangerous. Potassium helps to balance sodium in the cells and too little causes high amounts of sodium in the blood. Another risk factor is too little vitamin D. Although researchers aren’t entirely sure why, people with lower levels of vitamin D are more likely to have high blood pressure. The best way to lower the risk of high blood pressure is to eat a balanced diet rich in fresh fruits, vegetables, low-fat dairy products and whole grains and to eliminate high-fat foods. Also, limit the amount of processed foods, such as crackers, cookies and canned foods to lower the amount of sodium in the diet.

Weight – Being overweight can be a risk factor for high blood pressure. When a person is overweight, the body needs more oxygen and nutrients and the heart has to pump harder in order to supply the body with these necessities. Even losing a few pounds can make a difference in blood pressure. The weight on the scale may not be accurately telling the whole weight story, though. Experts now feel that waist size is a better measurement of weight than the scale. Women with a waist size of over 30 inches and men with a waist size of over 40 inches are considered to be overweight. Eating a balanced, healthy diet along with adding an exercise program is a good way to keep weight down and reduce the risk of high blood pressure.

Exercise – Exercise is important for weight control, lowering the heart rate and reducing stress. People who do not exercise are more likely to have a higher heart rate, which makes the heart work harder with each contraction. Exercise helps lower a person’s resting heart rate. Exercise also helps to lower stress and elevate mood. The American Heart Association suggests getting at least 2.5 hours of exercise each week and adding some strength training to the exercise routine.

Limit or Stop Unhealthy Habits – Using tobacco in any form or drinking alcohol can increase the risk of high blood pressure. Every time a person smokes, blood pressure raises temporarily. In addition, the chemicals in the cigarettes can cause damage to the artery walls, causing them to narrow and increase blood pressure. Alcohol also increases blood pressure by releasing hormones that increase blood flow and heart rate. People who are concerned about high blood pressure should stop smoking and limit alcohol consumption to no more than two drinks a day.

Stress

Stress – Chronic stress can increase blood pressure and cause damage the arteries. Many times, people who have high stress turn to smoking, drinking alcohol or overeating in order to calm their stress. The best way to calm stress is to begin an exercise program. It is also important to learn stress-relieving techniques to help lower stress in the moment. Taking deep breaths or walking away from the stressful situation for even five minutes before returning to it can help to lower the heart rate. Lowering risk factors for high blood pressure is important for overall health. High blood pressure can lead to damaged arteries, heart attack or stroke, so it is important to learn ways to reduce the risk of developing it. By lowering the risk factors, a person can lower their risk of developing high blood pressure now and as they grow older.

Laser Teeth Whitening for the Everyday Person

Laser Teeth Whitening for the Everyday Person

Have you ever thought about your smile and what it means to others? Teeth whitening is a good idea to improve your overall look with a white and clean smile. Everybody on TV and the movies always have shining white teeth, in reality that is not possible unless you are willing to shell out a lot of money for veeners, look at here now.

drugstore you may notice that tooth whitening products

The next time you go to a mall or drugstore you may notice that tooth whitening products are everywhere, there may be special gum, toothpaste or special teeth whiteners. But most of them don’t work very well some of them take months for it to take effect. An alternative more efficient method is to use a laser whitening method which takes about one hour for it to take effect, you may ask yourself if the movie stars use laser whitening to whiten their teeth?

Well actually they use veeners on their teeth to provide a constant shining white color. But for the everyday person veeners may not be the best choice, in reality not everyone’s teeth are shining white, unless of course they eat non-staining foods and water their whole life. If you are interested in whitening your teeth most teeth whitening professionals are more than glad to provide information, there are many types of teeth whitening for many people. Most likely your dentist provide teeth whitening services if not there is a growing population of teeth whitening professionals who specialize in teeth whitening.

The one drawback of laser teeth whitening is that they most likely did not last a long time and the teeth will be stained again especially if you smoke or drink lots of coffee. But it may be worth it as results are instantaneous and if you do not smoke or drink coffee, it may last months. Different laser teeth whitening methods exist and all of them have different effects and side effects, the best laser teeth whitening method would be one that not only cleans your teeth and whitens it, but make your teeth healthier as well.

There may be some negative side effects of laser teeth whitening such as teeth numbness or teeth sensitivity, most dentist or laser teeth whitening professionals can provide you information about these side effects and possible dangers, so make sure to always ask your dentist or teeth whitening specialist questions.

laser teeth whitening is bad for your teeths health

There are are people who think that laser teeth whitening is bad for your teeths health and the best way to whiten your teeth is to brush your teeth everyday three times a day, but there has not been any proven scientific tests that prove laser teeth whitening is negative to your health, but of course if you do not want to go to the dentist every couple of months to get your teeth whitened there are many other options such as teeth strips that you put on your teeth before you sleep, whitening paste that you put on your teeth, or just teeth whitening toothpaste. Whatever the choice, a good smile is a clean smile.

Astronomy How To: The Meade LX200GPS Schmidt-Cassegrain Telescope

The Meade LX200GPS Schmidt-Cassegrain Telescope

The Meade LX200 line of telescopes is easy to use, accurate, and scientifically stable. These telescopes are available in aperture ranges from 8” to 16”. While the larger telescopes (12” or greater) are quite heavy and permanently mounting them is recommended, they all are equipped with sophisticated optics which are quality control tested before they are sold and shipped.

Introduction to Telescopes

To briefly describe the various types of telescopes, they primarily come in two different types: reflectors and refractors. The primary difference in reflector telescopes and refracting telescopes is that reflectors use mirrors to focus light to a focal point and refractors use a glass lens. Both of these telescopes are excellent for astronomical observing.

Reflector Telescopes

Reflector Telescopes

Reflector telescopes, those which contain a mirror to focus light, are normally cheaper when compared to aperture size of refractor telescopes. The telescope aperture is the diameter of the primary mirror or lens within the telescope. This determines their “light gathering” power, see more.

The reason reflectors are cheaper than refractors is that mirrors are much easier to build and are more constructively stable than large lenses. A standard 10” reflector can be purchased for about the same price as a quality 4” refracting telescope. Another advantage of reflecting telescopes over refracting telescopes is that they are better suited for viewing deep space objects such as nebula and galaxies.

Refracting Telescopes

As mentioned earlier, refractors use lenses to focus light instead of a mirror. These telescopes are more expensive than reflectors – when compared to aperture – but these telescopes are preferred over reflector telescopes when observing planets or the moon. Due to many refractors having long focal lengths, the tubes (or body) of these telescopes can be quite long making these telescopes a bit difficult to transport. Still, refracting telescopes are probably more common with the backyard astronomer.

The Meade LX200 GPS Schmidt-Cassegrain Telescope

Meade Telescopes produces a telescope line called the LX200. The most common of these telescopes is the LX200 GPS – meaning this particular telescope has a built-in GPS unit which is capable of detecting its location and automatically setting the internal clock time. The LX200 optical tube is mounted on a fork mount, allowing it to be pointed nearly anywhere in the sky. An equatorial “wedge” can also be purchased for the LX200 fork mount, allowing the telescope to be used for astrophotography purposes.

The LX200 Schmidt-Cassegrain telescopes are based on the reflector (or mirror) design – except these telescopes use a “corrector lens”, a primary mirror, and a secondary mirror to focus the light. This design basically “folds” the telescope making it much shorter and easier to transport. The 12” LX200’s tube length is only around 24” – making it easier to handle.

The LX200 is also capable of using standard D-cell batteries or the supplied power cord can be used and plugged into a standard 120 volt power supply.

Meade LX200 GPS System

The Meade LX200 GPS system is a wonderful addition by Meade. This unit has been installed in these telescopes for several years. From the beginner to serious amateur astronomer – this is a great function! When the telescope is “powered up” you can manually obtain a “GPS fix” or the telescope computer can be manually set to do this automatically each time you turn the telescope on.

The Meade LX200 Optics

There are several different styles of optics available for the LX200. The optics in the original LX200 was considered “standard” optics. When the LX200 GPS model was developed, two choices were available for mirror coatings – standard or Ultra-High Transmission Coatings (UHTC). The UHTC optics cost just a little more, but they added an extra 10% light-gathering power. Well worth the money spent.

Other optics styles are also available for the newer LX200 line of telescopes, including the Advanced Coma-Free (ACF) optics which provides a well balanced image throughout the entire field of view. This optical system works very well for those who rather use their telescope for astrophotography. The ACF line of mirrors allows stars or other celestial objects to focus nicely at the very edge of the field of view. Without the ACF optics, those objects normally have a “bent” or unaligned appearance. If you are primarily interested in astrophotography, you might want to look into Meade’s ACF line of LX200 telescopes.

The Telescope Mount

The Telescope Mount

The LX200 telescopes are mounted on a fork mount. A fork mount basically looks like a “two-prong” fork with the telescope tube mounted inside. A fork mounted telescope can point nearly anywhere in the sky – unlike the German Equatorial Mount. While quality German equatorial mounts are very stable, they must perform a Meridian Flip when the pointing reaches the zenith (the point of the sky that is directly above). This can be time consuming.

Some people will add many additions to their telescopes focal point such as focal reducers, Digital SLR cameras, CCD Imagers, and a number of other components. When using these on a fork mounted telescope, take caution of the clearance they have between the base of the fork mount and the telescope because impact can occur.

The LX200 Telescope Computer and Computer Control

All styles of LX200 telescopes are equipped with an on-board computer system. The telescope is controlled with a “hand paddle” which contains the “brains” of the telescope. Thousands of pre-programmed targets, set-up options, custom programmable features, various tracking rates, and tons of other goodies are pre-installed in the hand paddle. The hand paddle even has a light and can even show you what the telescope temperature is. The LX200 can be completely controlled with this hand paddle, but for more options, the LX200 can also be easily connected to a personal computer.

The LX200 will connect to your personal computer via serial port. By doing this, you can control the telescope with your computer with many planetarium programs – such as TheSkyX. If you choose this option and the telescope has been properly set-up, you can simply “point and click” an object on your computer monitor and send the telescope to the object.

Connecting a Camera or CCD to the Telescope

The LX200 telescopes are specially designed for astrophotography. These telescopes provide excellent tracking and are very stable – making astrophotography fairly easy with a little experience. Lately, with the cost of DSLR camera’s dropping, these cameras are commonly being used on the LX200’s for astrophotography. According to the camera brand and style, you will need a special connector to attach the camera to the telescope. These are cheap and readily available on many Websites pertaining to astrophotography.

Professionally designed CCD imagers are also commonly used on LX200 telescopes. Many brands are available, but my experience in these cameras has been limited to the SBIG brand. These cameras are capable of “auto-guiding” via a cable connection from the camera to the telescope. This style of camera can auto-guide due to the fact that they actually have two CCD’s built into the camera body. One CCD monitors the tracking of the scope (making very fine adjustments to the telescope drive), while the other CCD is imaging your target.

Final Words on the Meade LX200 GPS Telescope

Final Words on the Meade LX200 GPS Telescope

From my own experience of using the Meade LX200 GPS telescope (which has been five years now), this is a great telescope. My personal LX200 GPS is the 12” model which, in my opinion,,is not too small or too large. I’ve never had any major issues with the telescope and it has provided me with thousands of images of planets, nebula, galaxies, stars, comets, and asteroids. If I ever decided to upgrade to a larger telescope, I would definitely purchase another Meade LX200 line of telescopes.

2010 Porsche Panamera Car Review

2010 Porsche Panamera Car Review

Porsche has always been great at giving us amazing looking two door coupes. Now, they say, there’s a new kid on the block, and they call it a four door coupe. Come on, a four door coupe? It’s been established a long time ago that four door cars are called “sedans” or “saloons.” Here we have, a four door coupe. Now, Porsche isn’t the only exotic car company that does that. Aston Martin has joined in, and so has Lamborghini! Now, there’s a reason why all of the companies mentioned above are mostly have two doors and two seats – and the reason is that you’ll need to sell your kids, and maybe even your wife, or husband, to be able to pay off the astronomical costs that come with owning one of these! So, why bother?

Porsche Panamera Car Review

Now, Jaguar, Mercedes, Audi, Maserati, and may others have done a great job making four door sedans! Notice I used the word “sedan” because that’s what they are. Four door cars made for people to fit int he front, and in the back. Now, I’m not buying this whole four door coupe thing because I’m not a product of marketing. In fact, I think it’s a shame that names like Porsche, Aston Martin, and Lamborghini have gone after four-door models, and even had the tenacity to call them “coupes!”

Enough about the whole four door coupe thing, and let’s move on to the Panamera. And I’ll be the first to say that I don’t like it one bit. It looks like a hatchback that had its rear pushed out a bit. It certainly doesn’t look like a coupe. They say that the sloping roof is what gives it a “coupe” characteristic, but I just can’t see it. Which ever angle I look at it, it either looks like a squashed mini-van, a hatchback, or a four door saloon.

But that’s not even the worst part. The car doesn’t look half bad, until you look at the rear. Good grief! It looks like a giant frog! Now, I know a few people who always say that all Porsche cars look like frogs, and I couldn’t agree with them, but on this one, they’re absolutely right!

I’m sure that the car feels great once you’re on the inside. It’s got leather seats, all the bells and whistles of a luxury saloon. But for some reason, Porsche has decided that instead of very nice looking materials like aluminum, they should fit it with a plastic dashboard. Are they insane? Many people will buy the Panamera and feel worthless after about a thousand or so moles!

The next aspect of the car is the engine. Or should I say, the range of engines. Base engine sports a 6 cylinder V-type engine. So now we know that it’s not going to have 500 horsepower, and it’s probably going to be something for an old grandma who is retired, and will do 35 miles per hour on the interstate all the way home, or an old man with arthritis who can’t handle a high performance vehicle. Now the cure for that is a V8 engine which will give it considerably more power. But why isn’t it V8 as standard? A man would buy the Panamera with a V6 and his kids, if he’s rich enough to keep them, would laugh at him when somebody on a Civic flies by. And if he buys a V8 Panamera, he won’t have to worry about his kids puking all over the leather, because they would have puked on his lawn, his flower bed, and the car itself before they even get in. By that time, they won’t have anything to puke on the very expensive leather with. But they’ll be sick all the way.

Porsche Panamera Car

And now, the worst part about the Panamera – the price. $125,000-$170,000! I’m sorry, but I’d rather buy a 911 and a house, or maybe, just maybe, I’ll buy a Lamborghini and remain homeless, but at least I’ll do it in style. The Panamera should be in the $40-50 thousand range so then people who buy it would actually afford to keep their kids, and take them out on a nice trip; that will eventually be ruined by his children’s breakfast.

Texting Goes Extinct as WhatsApp Dominates

Texting Goes Extinct as WhatsApp Dominates

The new era of internet technology has made everyone tech savvy and hungry for more applications for all kinds of operating systems for devices. The dotcom revolution not only motivated people to start using the cloud for business purposes but even encouraged businessmen to think differently and use the cloud for marketing and publicity for costs much lower than usual. Companies now engage in social media engagement techniques to increase the web traffic. Not only have existing businesses expanded but there were many newcomers that are now considered world’s biggest and most revolutionising firms. Facebook has changed the way people, particularly old friends keep in touch whereas Twitter has changed the way celebrities keep their fans gossiping about them.

WhatsApp Dominates

 Another important application that hit the cloud few years ago changed the way people use telecommunication services. To keep in touch with loved ones, people used SMS and MMS services of networks which cost people dearly. However, WhatsApp came to the rescue that changed the instant messaging scene of the cloud world. With free unlimited messages that cost nothing but less than a mega byte from the user’s data packs. Also, when somebody first downloads and installs the application on the phone, WhatsApp Inc. does not charge the user at all. And after a year of service, continuation charges are only up to a dollar per year. This humongous reduction in costs have made more and more people use the service and today WhatsApp has over billions of users and every day the company is upgrading their services to achieve their goal of unlimited end-to-end communication between different people across the world. Recently, WhatsApp even upgraded their service to voice chatting which enables users to exchange voice messages over the phone. This application is compatible with almost every operating system present out there, with Android, iOS, RIM and Windows being the most used ones. An icing on the cake is the ability of this application to exchange pictures, videos or contacts over the normal chat interface itself. There is no word limit and people can send as long messages they want without worrying about the word limit like in SMS services. The only requirement for people is to own a smartphone with a 2G or 3G connection that support internet services on the move.  

Very few applications have become as successful as WhatsApp but one thing that has made the success story of this application is the vision of the founders Jam Koum and Brian Acton to enable unlimited free communication to users without the hassle of advertisements popping up again and again. Also, the fact that no account needs to be created while initiating the app is also something that attracted so many users. It is one of the first of its kind to offer real time messaging over international borders without any hidden costs and it works on any modern smartphone device. It also provides high security by encrypting messages using open source chat protocol XMPP.

Carnitine Palmitoyltransferase Deficiency

Carnitine Palmitoyltransferase Deficiency

An uncommon genetic defect causes the most common disorder of lipid metabolism involving skeletal muscle. Fatty acids are a major source of fuel for human cells. They must be oxidized within mitochondria to release their energy, but some fatty acids cannot enter the mitochondria without first being joined to carnitine, an amino acid-like molecule.

Carnitine palmitoyltransferase, an enzyme that is embedded in the mitochondrial membrane, facilitates the transfer of long-chain fatty acids to the mitochondrial interior where they can be metabolized. Genetic deficiencies of carnitine palmitoyltransferase can cause a constellation of symptoms, get more info.

Carnitine Recycling Drives Long-Chain Fatty Acid Metabolism

Carnitine Recycling Drives Long-Chain Fatty Acid Metabolism

Two forms of carnitine palmitoyltransferase, or CPT, reside within the two-layered mitochondrial membrane. The first, CPT1, is located on the outer membrane, and it is responsible for hooking a long-chain fatty acid to a molecule of carnitine. The carnitine-fatty acid complex is then transported into the mitochondria, where the second form of carnitine palmitoyltransferase, called CPT2, detaches the carnitine from the fatty acid.

The fatty acid is then metabolized, while the carnitine diffuses out of the mitochondrion to the cellular cytoplasm where it can be attached to another fatty acid and repeat the process.

CPT1 Deficiency

Three distinct isoforms of CPT1 have been identified in liver, muscle and brain. According to a 2014 article in “Molecular Aspects of Medicine,” the only known CPT1 deficiency involves the liver isoform, and it is exceptionally rare. People with CPT1 deficiency experience recurrent episodes of muscle weakness, confusion and low blood sugar, and they often develop enlarged livers.

Episodes are often initiated by fasting, acute illnesses or other situations that demand increased use of fatty acids for energy. Because fatty acids are not being efficiently utilized, they can build up in various tissues and cause organ damage. People affected by CPT1 deficiency are at risk for nervous system damage, seizures, liver failure, coma and sudden death.

CPT2 Deficiency

CPT2 Deficiency

Defects in the gene that codes for production of CPT2 are much more common than those that impair CPT1 function. CPT2 deficiency manifests in at least three different forms. The lethal infantile form is uniformly fatal within the first few months of life. It usually presents within days of birth and is characterized by birth defects, liver and heart failure, abnormal cardiac rhythms, seizures and coma. The severe infantile form, which is the second type of CPT2 deficiency, typically presents within the first year of life and causes liver and heart failure, muscle weakness, seizures, headaches and abdominal pain. Sudden death may occur as the result of heart arrhythmias.

The adult “myopathic” form of CPT2 deficiency is the most common type. Symptoms can begin before puberty, but they may not begin until the six or seventh decade of life. Affected individuals experience intermittent attacks of weakness, muscle pain and myoglobinuria, which is brown-colored urine that results from the products of muscle damage appearing in the urine. Episodes are usually precipitated by prolonged exercise, cold exposure, fever or stress, but they can also be triggered by general anesthesia or sleep deprivation.

Treatment of Carnitine Palmitoyltransferase Deficiency

Some forms of CPT deficiency, such as the lethal infantile form, do not respond to treatment. Other forms can be partially ameliorated by restricting long-chain fatty acids in the diet, limiting total fat consumption to less than 20 percent of daily caloric intake, avoidance of fasting or prolonged exercise, supplementing with carnitine to help override the enzyme deficiency, increasing carbohydrate consumption and supplementing with medium-chain fatty acids to provide fuel molecules that don’t require CPT for transport.

Treatment of Carnitine Palmitoyltransferase Deficiency

According to Dr. Thomas Wieser, a neurologist at the Medical University of Vienna, Austria, people who suffer from CPT2 deficiency should avoid ibuprofen, general anesthesia, valproic acid and diazepam. Wieser also recommends genetic testing and counseling for affected individuals.

A Great Way to Generate All the Motivation You Need to Get Fit

A Great Way to Generate All the Motivation You Need to Get Fit

If you have difficulties motivated to continue your fitness program … or even on the starting block, but this article could change your life! Not at all … would It be too ambitious! However, there is a small device with little effort, all the motivation you need to go and start to offer your body a little more.

The pedometer, as you know, you may also want to make, and can even enjoy!

What … ? Train? Surely a mistake?

Well, not really. Please read on.

First So what is a pedometer?

There is a small compact device for measuring the number of steps.

And as far as number of measures taken in the exercise of their neighborhood, but also to measure your steps as you have to climb stairs, mow the lawn or shopping.

Second How it works

Second How it works

It is small enough to fit the waist and has a clock, a step measures each time your foot touches the ground.

Third How much?

Many were given pedometers as part of campaigns to local health authorities to move their bodies more.

If you can not find a campaign in your area you can buy a pedometer with a reasonable number of features for only $ 20.

4th What exactly do you do?

You should have a model that measures at least buy the number of steps, calories burned, distance, speed, you went and how long has your routine.

More expensive models, some or all of the following additional functions:

– A gentle voice that tells you what steps have you taken

– A pulse monitor

– A timer

– A radio and a headset so you can listen to your favorite radio station while walking

– A pass filters for increased accuracy

– A backlit, so watch your step counter in the dark.

5th How do I Set My Pedometer?

5th How do I Set My Pedometer

First, you need your height, weight and length step.

To reach the length of stride, the majority of the instructions will lead you to ask you to measure a distance, say 10 meters, and counting the steps you take to cover them. Divided by the total distance and gives the step half their length.

Once installed, simply follow the instructions to activate your desired settings, clip the pedometer to your belt and you’re ready to go.

6th How to take the readings?

At any time after you start your routine can stop you, open the pedometer and a measurement. Of course you should not very often, because it disrupts the rhythm of your walk.

But can an idea of what progress we make by getting the number of steps, distance, calories burned, and so on. You can move from one position to another in the press of a button.

7th How can I provide more motivation?

The good thing about using a pedometer is that one of the number of steps you have taken your daily goal to start thinking.

This leads to a “culture of walking and suddenly start up new possibilities for identifying a set distance.

If I had to be dragged kicking and screaming to an exercise routine, a pedometer is a device most importantly, you can use to enjoy your workouts.

It is so easy to use and able to transform the way we think fit. It can resist to the idea of a daily workout, your very excited and want to do discover more.

7th How can I provide more motivation

Why?

Because after using it for a while, they begin to understand that daily goals are not only feasible, but with a little more effort can be easily overcome.

Something that I thought was a routine is simple, because you know you can do it!

Have you ever thought possible? Well it is. Enter your pedometer and keep it carries. You can have a positive effect on your fitness and health.

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Breathwork is an active meditation technique that uses the breath to emotionally detox the body. If you've never experienced breathwork, it goes like this: you show up in comfortable clothing, lay down, close your eyes and listen to the instructions.

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